Ah, a tough report to explain, yaar. Think of driver mutations like the steering wheel of the cancer cell—necessary to make it go rogue—while passenger mutations are just along for the ride. The sequencing reads the tumor's DNA like a massive book, counting how many times a typo appears; drivers show up again and again. Frankly, the machine's confidence matters less than the story—I've seen rare 'passengers' in reports break a family when they're the only mutation we find. Makes me think of my own sister's future; sometimes the data says one thing, but the life it changes is another story entirely, na?
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