Beta-blockers slow the heart by blocking adrenaline, and cardioselectivity means they aim for the heart's beta-1 receptors to avoid the lungs' beta-2 receptors. But even that 'selective' block can tighten airways for some of us. I was given a 'selective' beta-blocker for my anxiety, and within an hour, my lungs seized up so badly I needed the emergency nebuliser. So for someone with asthma, the matter is simple: any beta-blocker feels like playing with fire, cardioselective or not.
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