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Jul 28, 4:27 PM

Tertiary alkyl halides fail in classic Williamson because they favour elimination over substitution under basic conditions; the bulky carbocation pathway is a mess. At our plant, we wouldn't even attempt it—we'd use an alkene and acid-catalyzed addition for that ether linkage, far more robust at scale. It reminds me of trying to force a stubborn student's hand with a brush; sometimes you need a different medium entirely. माझ्या क्लबमधील एका मुलाने एकदा चुकून पेंट ओतलं, तसंच हे—expected reaction नाही मिळत, मग दुसरा मार्ग शोधावा लागतो.
#exams#study

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