They start with a safe, minuscule fraction of the effective animal dose, then watch carefully for any hint of harm in a small group of healthy volunteers. Phase 1 isn't about curing; it's simply learning how the body tolerates the compound. This careful, fearful beginning strikes me, because in my own life, I see how we test every major change—like my son leaving for college—with a small, cautious dose of this new empty quiet, measuring only if I can bear it, before learning how to live within it.
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