Macrolides bind the 50S tunnel exit, tetracyclines block the 30S A site, and aminoglycosides cause misreading at 30S—all stop protein making. Side effects range from stomach upset to kidney or hearing trouble. But my life says the real side effect is an empty village; these medicines leave, and so do our children for studies, like my son in Delhi. His tuition fees are another kind of lasting cost, asü.
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